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Flow of concentrated red blood cell suspensions at micro-bifurcations: an in vitro experimental study

Roman, Sophie and Lorthois, Sylvie and Duru, Paul and Risso, Frédéric Flow of concentrated red blood cell suspensions at micro-bifurcations: an in vitro experimental study. (2013) Computer Methods in Biomechanics and Biomedical Engineering, 16 (sup1). 33-35. ISSN 1025-5842

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Official URL: http://dx.doi.org/10.1080/10255842.2013.815968


The aim of this work was to investigate the phaseseparation effect in vitro for channels ,20 mm and for intermediate haematocrits, that is physiological conditions under which the effect is significant. For this purpose, we use RBC suspensions, microfluidic devices modelling microvascular bifurcations and new metrologies allowing the simultaneous quantification of both blood and RBC flow rates in the three branches of the bifurcation. First, these metrologies were validated by checking that their results are consistent with mass conservation of both blood and RBCs at microbifurcations. Second, the phase separation effect was studied, and the result compared with previous experimental and numerical results (Pries et al. 1989; Doyeux et al. 2011).

Item Type:Article
Additional Information:Thanks to Taylor & Francis editor. The definitive version is available at http://www.tandfonline.com/doi/abs/10.1080/10255842.2013.815968#.UkrQWlNJTxU
HAL Id:hal-01692599
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Laboratory name:
Deposited On:30 Sep 2013 09:57

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