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Formation of nanosized strontium substituted hydroxyapatites

Gross, Karlis and Jersova, Anastasia and Grossin, David and Rey, Christian and Viksna, Arturs Formation of nanosized strontium substituted hydroxyapatites. (2012) IOP Conference Series: Materials Science and Engineering, 38 (1). ISSN 1757-8981

(Document in English)

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Official URL: http://dx.doi.org/10.1088/1757-899X/38/1/012032


Incorporation of specific elements into calcium phosphates offers the combination of a bioactive material and a therapeutic effect. This is important for improving the integration of implants as well as treating medical conditions. Strontium is a suitable candidate and displays the ability to stimulate bone growth and reducing bone resorption. This study investigated the formation of strontium carbonated hydroxyapatite nanoparticles from an amorphous phase. Crystallization of carbonated hydroxyapatite occurred at 585 oC, but samples with an intended 25% and 75% replacement of calcium with strontium crystallized at 624 oC. Heat treatment at the crystallization temperature revealed that strontium free apatite does not crystallize in 5 minutes, but an increasing strontium concentration leads to a higher rate of crystallization. X-ray diffraction patterns suggest that it may be difficult to include strontium, but higher strontium concentrations are possibly included with ease in the lattice. This work has produced a nanosized apatite accompanied by an amorphous phase after a short heat-treatment time. This offers a range of features that collectively show great promise for significantly enhancing the release of strontium for improved bone therapeutic effects.

Item Type:Article
Additional Information:Thanks to IOP editor. The definitive version is available at http://iopscience.iop.org/. This in an open access title - started 2009. Publisher's version/PDF may be used
HAL Id:hal-03528019
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Other partners > Riga Technical University (LATVIA)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Other partners > University of Latvia (LATVIA)
Laboratory name:
Deposited On:15 Jul 2013 08:39

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