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CCVD Synthesis of Carbon-Encapsulated Cobalt Nanoparticles for Biomedical Applications

Lukanov, Petar and Anuganti, Vijay K. and Krupskaya, Yulia and Galibert, Anne-Marie and Soula, Brigitte and Tîlmaciu, Carmen and Velders, Aldrik H. and Klingeler, Ruediger and Büchner, Bernd and Flahaut, Emmanuel CCVD Synthesis of Carbon-Encapsulated Cobalt Nanoparticles for Biomedical Applications. (2011) Advanced Functional Materials, 241 (18). 3583-3588. ISSN 1616-301X

(Document in English)

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Official URL: http://dx.doi.org/10.1002/adfm.201100364


Carbon-encapsulated ferromagnetic Cobalt nanoparticles (Co@C) have been synthesized by catalytic chemical vapour deposition (CCVD). The nanoparticles, mainly ranging between 10 and 15 nm, are tightly encapsulated by 2–3 concentric graphitic carbon shells and protected from oxidation. Because of their magnetic properties (saturation magnetization of 106 emu/g and a coercivity HC of 250 Oe), Co@C nanoparticles have been investigated for hyperthermia application. Although the observed values of the specific absorption rate (28.7 W/gCo@C at 30 kA/m and 215.4 W/gCo@C at 70 kA/m) are slightly lower than required in actual hyperthermia therapies, the observed strong heating effect provides a very promising starting point for future clinical application. It is also demonstrated that these nanoparticles can at the same time be used for magnetic resonance imaging (MRI) with an efficiency comparable to commercially available T2 contrast agents.

Item Type:Article
Additional Information:Thanks to John Wiley & Sons editor. The original version is available at http://onlinelibrary.wiley.com/ The original PDF of the article can be found at Advanced Functional Materials website: http://onlinelibrary.wiley.com/doi/10.1002/adfm.201100364/abstract
HAL Id:hal-03472026
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Other partners > Universität Heidelberg (GERMANY)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Other partners > Leibniz-Institut für Festkörper- und Werkstoffforschung (GERMANY)
Other partners > University of Twente (NETHERLANDS)
Laboratory name:
Deposited On:31 Aug 2012 14:56

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