Délécouls-Servat, Karine and Bergel, Alain
and Basséguy, Régine
Membrane electrochemical reactors (MER) for NADH regeneration
in HLADH-catalysed synthesis: comparison of effectiveness.
(2004)
Bioprocess and Biosystems Engineering, 2. 205-215. ISSN 1615-7591
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(Document in English)
PDF (Author's version) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader 350kB |
Official URL: http://dx.doi.org/10.1007/s00449-004-0356-2
Abstract
Two membrane electrochemical reactors(MER) were designed and applied to HLADH-catalysed reduction of cyclohexanone to cyclohexanol. The regeneration of the cofactor NADH was ensured electrochemically, using either methyl viologen or a rhodium complex as electrochemical mediator. A semipermeable membrane (dialysis or ultra-filtration) was integrated in the filter-press electrochemical reactor to confine the enzyme(s) as close as possible to the electrode surface. When methyl viologen was used, the transformation ratio of cyclohexanone varied from 0 to 65% depending on the internal arrangement of the reactor. Matching the reactor configuration to the reaction system was essential in this case. With the rhodium complex, the ultra-filtration MER was tested in continuous and recycling configurations. The best conditions led to 100% transformation of 0.1 L volume of 0.1 M cyclohexanone after 70 h with the recycling mode. Finally, the performances of the reactors are discussed with respect to different evaluations of the production yields.
Item Type: | Article |
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Additional Information: | The original publication is available at www.springerlink.com http://www.springerlink.com/content/x0wq9arprcfylfkp/?p=0103239e7e7049cd9dc25331544c5ab1&pi=1 |
Audience (journal): | International peer-reviewed journal |
Uncontrolled Keywords: | |
Institution: | Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE) Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE) French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE) |
Laboratory name: | Laboratoire de Génie Chimique - LGC (Toulouse, France) - Bioprocédés et systèmes microbiens (BioSyM) |
Statistics: | download |
Deposited On: | 21 Feb 2008 08:28 |
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