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Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Nouvel, Laurent-Xavier and Kassa-Kelembho, Eric and Dos Vultos, Tiago and Zandanga, Germain and Rauzier, Jean and Lafoz, Carmen and Martin, Carlos and Blazquez, Jesus and Talarmin, Antoine and Gicquel, Brigitte Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic. (2006) Emerging Infectious Diseases, 12 (9). 1454-1456. ISSN 1080-6040

(Document in English)

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Official URL: http://www.cdc.gov/ncidod/EID/vol12no09/06-0361.htm


We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.

Item Type:Article
Additional Information:Thanks to the Emerging Infectious Diseases Journal. The definitive version is available at http://www.cdc.gov/ncidod/EID/ The original PDF of the article can be found at http://www.cdc.gov/ncidod/EID/vol12no09/pdfs/06-0361.pdf
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:Other partners > Centro Nacional de Biotecnología (SPAIN)
Other partners > Institut Pasteur (FRANCE)
Other partners > Changsha University (CHINA)
Other partners > Universidad Zaragoza (SPAIN)
Laboratory name:
Deposited On:28 Jul 2010 12:39

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