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Cyclophosphamide removal by nanofiltration and reverse osmosis membranes - effect of water matrix properties

Albasi, Claire and Causserand, Christel and Dorandeu, Christophe and Faucet-Marquis, Virginie and Marion, Bénédicte and Pfohl-Leszkowicz, Annie and Wang, Li Cyclophosphamide removal by nanofiltration and reverse osmosis membranes - effect of water matrix properties. (2009) In: 2nd International Congress on Green Process Engineering,2nd European Process Intensification Conference, 14-17 June 2009, Venise,Italie .

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The rejection of cyclophosphamide (CP) by nanofiltration (NF) and reverse osmosis (RO) membranes from ultrapure (Milli-Q) water and membrane bioreactor (MBR) effluent was investigated. Experimental results showed that the RO membrane provided excellent rejection (>90%) under all operating conditions. Conversely, efficiency of CP rejection by NF membrane was poor: in the range of 20-40% from Milli-Q water and around 60% from MBR effluent. Trans-membrane pressure, initial CP concentration and ionic strength of the feed solution had almost no effect on CP retention by NF. On the other hand, the water matrix proved to have a great influence: CP rejection rate by NF was clearly enhanced when MBR effluent was used as the background solution. Membrane fouling and interactions between the CP molecule and water matrix appeared to contribute to the higher rejection of CP.

Item Type:Conference or Workshop Item (Speech)
Additional Information:This article is publied in the CDrom : Proceedings,14-17 June 2009,Venice-Italy.
Audience (journal):International peer-reviewed journal
Audience (conference):International conference proceedings
Uncontrolled Keywords:
Institution:Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Laboratory name:
Deposited On:08 Jul 2009 13:26

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