Bernard, David and Pascalie, Jonathan
and Mondésert, Odile and Ducommun, Bernard and Duthen, Yves
and Cussat-Blanc, Sylvain
and Lobjois, Valérie
Optimization of synchronization experiments using a checkpoint-oriented cell cycle simulator.
(2018)
In: Toulouse Onco Week (TOW 2018), 3 February 2018 - 7 February 2018 (Toulouse, France).
(Unpublished)
|
(Document in English)
PDF (Author's version) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader 139kB |
Abstract
Cell cycle synchronization at a specific stage is often an essential requirement to investigate biological events and mechanisms using the large panel of molecular and cellular biology technologies. Optimization of the synchronization parameters is most of the time neglected, which could result in experimental time wasting or even in erroneous conclusions. Here we report the development of a cell cycle checkpoint-oriented simulator, based on agent-based modeling (ABM), that reproduces the dynamic behavior of a proliferating cell population and its response to checkpoint activation.
Item Type: | Conference or Workshop Item (Poster) |
---|---|
HAL Id: | hal-02947736 |
Audience (conference): | National conference proceedings |
Uncontrolled Keywords: | |
Institution: | French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE) Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE) Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE) Université de Toulouse > Université Toulouse - Jean Jaurès - UT2J (FRANCE) Université de Toulouse > Université Toulouse 1 Capitole - UT1 (FRANCE) Other partners > Centre Hospitalier Universitaire de Toulouse - CHU Toulouse (FRANCE) |
Laboratory name: | |
Statistics: | download |
Deposited On: | 09 Sep 2020 08:17 |
Repository Staff Only: item control page