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Nanostructured calcium phosphates for hard tissue engineering and nanomedicine

Drouet, Christophe and Rey, Christian Nanostructured calcium phosphates for hard tissue engineering and nanomedicine. (2020) In: Nanostructured Biomaterials for Regenerative Medicine. (Woodhead Publishing Series in Biomaterials). Woodhead Publishing, 223-254. ISBN 978-0-08-102594-9

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Official URL: https://doi.org/10.1016/B978-0-08-102594-9.00008-5


Calcium phosphates are major minerals associated with living organisms, whether as extracellular mineralizations or intracellularly, including with nanometric dimensions. Nanocrystalline apatites are one particularly relevant family of compounds of biological relevance; and approaches have been developed to synthesize and characterize biomimetic analogs in view of applications in medicine. One of the most interesting properties of apatite nanocrystals is their capacity to interact with each other via their hydrated ionic surface layers. But the nanocrystals can also interact strongly with different substrates and (macro)molecules. The high reactivity of these compounds can also be tailored via appropriate associations with ions and (bio)molecules to convey additional functionalities to the derived biomaterials. This opens the way to biomedical applications, not only in the field of bone regeneration, but also more recently in nanomedicine where the bioactivity and intrinsic biocompatibility of these bio-inspired compounds are increasingly appealing.

Item Type:Book Section
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
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Deposited On:07 Jul 2020 08:11

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