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Blood suspension in a network

Lorthois, Sylvie Blood suspension in a network. (2019) In: Dynamics of blood cell suspensions in microflows. CRC Press, Boca Raton, 257-286. ISBN 9781138032057

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Official URL: https://www.taylorfrancis.com/books/e/9781315395142/chapters/10.1201/b21806-8


This chapter presents key elements about the architectural organization of microvascular networks. It considers the suspension behavior of blood in simple components of a network, from single vessels to bifurcations. Many excellent reviews on blood flow in microvascular networks are available, mainly based on the contribution of pioneers who investigated superficial two-dimensional networks, such as the cremaster muscle or the mesentery, through a combination of intravital microscopy, model experiments and mathematical modeling. Microvascular networks are able to ensure adequate blood supply, feeding every cell in peripheral tissues under a wide range of physiologic conditions and varying metabolic needs. Microvascular bifurcations are the smallest architectural components of a microvascular network where hematocrit heterogeneities can be observed. With plasma, the formation of loose Red blood cells (RBC) aggregates in the sample makes the suspension less uniform. In the regime of microcirculation, the size of RBCs is not negligible compared to the size of blood vessels, which breaks off the continuum assumption.

Item Type:Book Section
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Laboratory name:
European Commission - National Institute of Neurological Disorders and Stroke of the National Institutes of Health - NINDS/NIH (USA) - National Cancer Institute of the National Institutes of Health - NCI/NIH (USA)
Deposited On:21 Apr 2020 16:53

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