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Numerical simulation of magnetic resonance angiographies of an anatomically realistic stenotic carotid bifurcation

Lorthois, Sylvie and Stroud-Rossman, Jenn and Berger, Stanley and Jou, Liang-Der and Saloner, David Numerical simulation of magnetic resonance angiographies of an anatomically realistic stenotic carotid bifurcation. (2005) Annals of Biomedical Engineering, 33 (3). 270-283. ISSN 0090-6964

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Official URL: https://doi.org/10.1007/s10439-005-1730-1


Magnetic Resonance Angiography (MRA) has become a routine imaging modality for the clinical evaluation of obstructive vascular disease. However, complex circulatory flow patterns, which redistribute the Magnetic Resonance (MR) signal in a complicated way, may generate flow artifacts and impair image quality. Numerical simulation of MRAs is a useful tool to study the mechanisms of artifactual signal production. The present study proposes a new approach to perform such simulations, applicable to complex anatomically realistic vascular geometries. Both the Navier-Stokes and the Bloch equations are solved on the same mesh to obtain the distribution of modulus and phase of the magnetization. The simulated angiography is subsequently constructed by a simple geometric procedure mapping the physical plane into the MRA image plane. Steady bidimensional numerical simulations of MRAs of an anatomically realistic severely stenotic carotid artery bifurcation are presented, for both time-of-flight and contrast-enhanced imaging modalities. These simulations are validated 3by qualitative comparison with flow phantom experiments performed under comparable conditions.

Item Type:Article
HAL Id:hal-03599549
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Other partners > Harvey Mudd College - HMC (USA)
Other partners > University of California - UC Berkeley (USA)
Other partners > University of California, San Francisco - UCSF (USA)
Laboratory name:
Deposited On:12 Dec 2019 09:55

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