Till, Ugo and Gibot, Laure and Mingotaud, Anne-Françoise and Mingotaud, Christophe and Rols, Marie-Pierre and Gaucher, Mireille and Violleau, Frédéric and Vicendo, Patricia
Polymeric self-assemblies for photodynamic therapy: A critical approach.
(2017)
Photodiagnosis and Photodynamic Therapy, 17. A23-A24. ISSN 1572-1000
|
(Document in English)
PDF (Author's version) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader 274kB |
Official URL: https://doi.org/10.1016/j.pdpdt.2017.01.053
Abstract
The work presented here suggests a new approach in the critical development of polymeric nanovectors for photodynamic therapy (PDT) against cancer. Whereas hundreds of studies quickly jump forward from formation of self-assemblies to biological application without having a thorough examination of the vector solution, we suggest having a parallel assessment of formation/characterization of the nanovectors and biological activity [1]. This is possible by first using a careful physical chemistry characterization of the vectors by both batch techniques (light and neutron scattering, electron microscopy, atomic force microscopy) and Asymmetrical Flow Field-Flow Fractionation (AsFlFFF) coupled to adequate detectors (refractometry, light scattering) [2]. This enables us to fully characterize the vectors regarding purity, size and zeta potential.
Item Type: | Article |
---|---|
HAL Id: | hal-03511855 |
Audience (journal): | International peer-reviewed journal |
Uncontrolled Keywords: | |
Institution: | French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE) Université de Toulouse > Ecole d'Ingénieurs de Purpan - EIP (FRANCE) Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE) French research institutions > Institut National de la Recherche Agronomique - INRA (FRANCE) Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE) |
Laboratory name: | |
Statistics: | download |
Deposited On: | 27 Nov 2019 09:26 |
Repository Staff Only: item control page