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Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications

Karacan, Ipek and Macha, Innocent Jacob and Choi, Gina and Cazalbou, Sophie and Ben-Nissan, Besim Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications. (2017) Key Engineering Materials, 758. 120-125. ISSN 1662-9795

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Official URL: https://doi.org/10.4028/www.scientific.net/KEM.758.120

Abstract

The biodegradable and biocompatible antibiotic containing thin film composites are very appropriate biomaterials as coating materials for dental implants because of their adjustable drug loading and release rates for the prevention of implant related infections. Coralline hydroxyapatite (HAp) was loaded with gentamicin antibiotics and combined with a biodegradable polylactic acid (PLA) to form thin film composites. PLA-HAp, PLA-Gentamicin (GM) and PLA-HAp-GM composites were produced, and their dissolution studies were carried out in phosphate buffered saline under SINK conditions. It was observed that the coatings could be efficiently applied to titanium dental implants and the drug release rates can be efficiently controlled.

Item Type:Article
HAL Id:hal-02401568
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Other partners > University of Dar es Salaam (TANZANIA)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Other partners > University of Technology, Sydney - UTS (AUSTRALIA)
Laboratory name:
Funders:
Horizon 2020 European Commission - Australian Academy of Science
Statistics:download
Deposited By: Yves MOMBOISSE
Deposited On:10 Dec 2019 08:45

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