Karacan, Ipek and Macha, Innocent Jacob and Choi, Gina and Cazalbou, Sophie
and Ben-Nissan, Besim
Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications.
(2017)
Key Engineering Materials, 758. 120-125. ISSN 1662-9795
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(Document in English)
PDF (Author's version) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader 1MB |
Official URL: https://doi.org/10.4028/www.scientific.net/KEM.758.120
Abstract
The biodegradable and biocompatible antibiotic containing thin film composites are very appropriate biomaterials as coating materials for dental implants because of their adjustable drug loading and release rates for the prevention of implant related infections. Coralline hydroxyapatite (HAp) was loaded with gentamicin antibiotics and combined with a biodegradable polylactic acid (PLA) to form thin film composites. PLA-HAp, PLA-Gentamicin (GM) and PLA-HAp-GM composites were produced, and their dissolution studies were carried out in phosphate buffered saline under SINK conditions. It was observed that the coatings could be efficiently applied to titanium dental implants and the drug release rates can be efficiently controlled.
| Item Type: | Article |
|---|---|
| HAL Id: | hal-02401568 |
| Audience (journal): | International peer-reviewed journal |
| Uncontrolled Keywords: | |
| Institution: | French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE) Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE) Other partners > University of Dar es Salaam (TANZANIA) Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE) Other partners > University of Technology, Sydney - UTS (AUSTRALIA) |
| Laboratory name: | |
| Funders: | Horizon 2020 European Commission - Australian Academy of Science |
| Statistics: | download |
| Deposited On: | 10 Dec 2019 08:45 |
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