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Mathematical assessment of the role of environmental factors on the dynamical transmission of cholera

Kolaye, Gabriel and Bowong Tsakou, Samuel and Houé Ngouna, Raymond and Aziz-Alaoui, Moulay Ahmed and Cadivel, Martin Mathematical assessment of the role of environmental factors on the dynamical transmission of cholera. (2019) Communications in Nonlinear Science and Numerical Simulation, 67. 203-222. ISSN 1007-5704

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Official URL: http://doi.org/10.1016/j.cnsns.2018.06.023

Abstract

In this paper, we investigate the impact of environmental factors on the dynamical transmission of cholera within a human community. We propose a mathematical model for the dynamical transmission of cholera that incorporates the virulence of bacteria and the commensalism relationship between bacteria and the aquatic reservoirs on the persistence of the disease. We provide a theoretical study of the model. We derive the basic reproduction number R 0 which determines the extinction and the persistence of the infection. We show that the disease-free equilibrium is globally asymptotically stable whenever R 0 ≤1 , while when R 0 > 1 , the disease-free equilibrium is unstable and there exists a unique endemic equilibrium point which is locally asymptotically stable on a positively invariant region of the positive orthant. The sensitivity analysis of the model has been performed in order to determine the impact of related parameters on outbreak severity. Theoretical results are supported by numerical simulations, which further suggest the necessity to implement sanitation campaigns of aquatic environments by using suitable products against the bacteria during the periods of growth of aquatic reservoirs.

Item Type:Article
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Other partners > Saint Jérome catholic University Douala (CAMEROON)
Other partners > University of Douala (CAMEROON)
Other partners > Université du Havre - ULH (FRANCE)
Other partners > Université de Yaoundé I (CAMEROON)
Other partners > Université de Ngaoundéré (CAMEROON)
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Deposited On:07 Dec 2018 10:34

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