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Bifunctional silica nanoparticles for the exploration of Pseudomonas aeruginosa biofilm

Mauline, Léïla and Gressier, Marie and Hammer, Peter and Ribeiro, Sidney J. L. and Caiut, José Maurício A. and Menu, Marie-Joëlle and Roques, Christine Bifunctional silica nanoparticles for the exploration of Pseudomonas aeruginosa biofilm. (2016) In: 2016 IEEE Nanotechnology Materials and Devices Conference (NMDC), 9 October 2016 - 12 October 2016 (Toulouse, France).

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Official URL: https://doi.org/10.1109/NMDC.2016.7777158


Luminescent silica nanoparticles (LSNPs) are frequently employed for biotechnology applications mainly because of easy functionalization, photo-stability and biocompatibility. Bifunctional silica nanoparticles (BSNPs) are described here as new efficient tools for the understanding of a complex biological system such as biofilms. Photoluminescence is brought by the incorporation of a silylated ruthenium(II) complex, surface properties of the silica particles are designed by reaction with. BSNPs are fully characterized and Zeta potential and contact angle measurements exhibit various surface properties according to the functional groups. Confocal Laser Scanning Microscopy measurements show that the spatial distribution of these nanoparticles inside PAO1 biofilm depends more on their hydrophilic/hydrophobic characteristics than on their size.

Item Type:Conference or Workshop Item (Paper)
Additional Information:978-1-5090-4352-1
HAL Id:hal-01936999
Audience (conference):International conference proceedings
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Other partners > Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP / São Paulo State University (BRAZIL)
Other partners > Universidade de São Paulo - USP (BRAZIL)
Laboratory name:
Ministère de l'Enseignement Supérieur et de la Recherche - MESR
Deposited On:27 Nov 2018 17:43

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