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PNIPAM grafted surfaces through ATRP and RAFT polymerization: Chemistry and bioadhesion

Conzatti, Guillaume and Cavalie, Sandrine and Combes, Christèle and Torrisani, J. and Carrerre, N. and Tourrette, Audrey PNIPAM grafted surfaces through ATRP and RAFT polymerization: Chemistry and bioadhesion. (2017) Colloids and Surfaces B Biointerfaces, 151. 143-155. ISSN 0927-7765

(Document in English)

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Official URL: http://dx.doi.org/10.1016/j.colsurfb.2016.12.007


Biomaterials surface design is critical for the control of materials and biological system interactions.Being regulated by a layer of molecular dimensions, bioadhesion could be effectively tailored by polymersurface grafting. Basically, this surface modification can be controlled by radical polymerization, whichis a useful tool for this purpose. The aim of this review is to provide a comprehensive overview of therole of surface characteristics on bioadhesion properties. We place a particular focus on biomaterialsfunctionalized with a brush surface, on presentation of grafting techniques for “grafting to” and “graft-ing from” strategies and on brush characterization methods. Since atom transfer radical polymerization(ATRP) and reversible addition-fragmentation chain transfer (RAFT) polymerization are the most fre-quently used grafting techniques, their main characteristics will be explained. Through the example ofpoly(N-isopropylacrylamide) (PNIPAM) which is a widely used polymer allowing tuneable cell adhesion,smart surfaces involving PNIPAM will be presented with their main modern applications.

Item Type:Article
Additional Information:Thanks to Elsevier editor. The definitive version is available at http://www.sciencedirect.com The original PDF of the article can be found at : http://www.sciencedirect.com/science/article/pii/S0927776516308451
HAL Id:hal-01625967
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
French research institutions > Institut National de la Santé et de la Recherche Médicale - INSERM (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Other partners > Centre Hospitalier Universitaire de Toulouse - CHU Toulouse (FRANCE)
Laboratory name:
French National Research Agency
Deposited On:30 Oct 2017 08:12

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