Conzatti, Guillaume and Cavalie, Sandrine
and Combes, Christèle
and Torrisani, J. and Carrerre, N. and Tourrette, Audrey
PNIPAM grafted surfaces through ATRP and RAFT polymerization: Chemistry and bioadhesion.
(2017)
Colloids and Surfaces B Biointerfaces, 151. 143-155. ISSN 0927-7765
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(Document in English)
PDF (Author's version) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader 1MB |
Official URL: http://dx.doi.org/10.1016/j.colsurfb.2016.12.007
Abstract
Biomaterials surface design is critical for the control of materials and biological system interactions.Being regulated by a layer of molecular dimensions, bioadhesion could be effectively tailored by polymersurface grafting. Basically, this surface modification can be controlled by radical polymerization, whichis a useful tool for this purpose. The aim of this review is to provide a comprehensive overview of therole of surface characteristics on bioadhesion properties. We place a particular focus on biomaterialsfunctionalized with a brush surface, on presentation of grafting techniques for “grafting to” and “graft-ing from” strategies and on brush characterization methods. Since atom transfer radical polymerization(ATRP) and reversible addition-fragmentation chain transfer (RAFT) polymerization are the most fre-quently used grafting techniques, their main characteristics will be explained. Through the example ofpoly(N-isopropylacrylamide) (PNIPAM) which is a widely used polymer allowing tuneable cell adhesion,smart surfaces involving PNIPAM will be presented with their main modern applications.
Item Type: | Article |
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Additional Information: | Thanks to Elsevier editor. The definitive version is available at http://www.sciencedirect.com The original PDF of the article can be found at : http://www.sciencedirect.com/science/article/pii/S0927776516308451 |
HAL Id: | hal-01625967 |
Audience (journal): | International peer-reviewed journal |
Uncontrolled Keywords: | |
Institution: | French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE) Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE) French research institutions > Institut National de la Santé et de la Recherche Médicale - INSERM (FRANCE) Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE) Other partners > Centre Hospitalier Universitaire de Toulouse - CHU Toulouse (FRANCE) |
Laboratory name: | |
Funders: | French National Research Agency |
Statistics: | download |
Deposited On: | 30 Oct 2017 08:12 |
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