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Differential Transcriptional Response To Staphylococcus aureus Infection In Two Divergent Lines Of Sheep Selected On Milk Somatic Cell Score

Bonnefont, Cécile and Foucras, Gilles and Toufeer, Mehdi and Caubet, Cécile and Aurel, Marie-Rose and Robert-Granié, Christèle and Cunha, Patricia and Gilbert, Florence B. and Rainard, Pascal and Rupp, Rachel Differential Transcriptional Response To Staphylococcus aureus Infection In Two Divergent Lines Of Sheep Selected On Milk Somatic Cell Score. (2010) In: World Congress on Genetics Applied to Livestock Production, 1 August 2010 - 6 August 2010 (Leipzig, Germany).

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Abstract

The milk somatic cell score (SCS) is an indirect indicator of mastitis, currently used as a selection criterion of dairy ruminants that leads to decreased intra-mammary infection prevalence. In the present study, gene expression profiles after Staphylococcus stimulations were determined in three cell types of mastitis resistant and susceptible ewes. The comparisons of the lists of the differentially-expressed genes allowed identification of commonly-regulated genes among cell types. These results lead to identify a subset of genes involved in pathogen-related receptor signaling. These genes may play an important role in recognition of pathogens and may improve resistance to intramammary infections.

Item Type:Conference or Workshop Item (Paper)
HAL Id:hal-01521770
Audience (conference):International conference proceedings
Uncontrolled Keywords:
Institution:Université de Toulouse > Ecole Nationale Vétérinaire de Toulouse - ENVT (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
French research institutions > Institut National de la Recherche Agronomique - INRA (FRANCE)
Laboratory name:
Funders:
APIS-GENE
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Deposited By: Cecile BONNEFONT
Deposited On:12 May 2017 09:46

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