Chatelin, Robin and Anne-Archard, Dominique and Murris-Espin, Marlène and Sanchez, David and Thiriet, Marc and Didier, Alain and Poncet, Philippe Modeling Cystic Fibrosis and Mucociliary Clearance. (2017) In: Modeling of Microscale Transport in Biological Processes. Elsevier, Academic Press, 113-154. ISBN 978-0-12-804595-4
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Official URL: http://dx.doi.org/10.1016/B978-0-12-804595-4.00005-5
Abstract
This chapter considers the investigation of airway clearance effi.ciency and dysfonction using rheological meastll'ements, modeling and simulations of mucus flows. The work is mainly dedicated to the respiratory epithelium dysfunction subsequently to the consumption of cilia-inhibiting drugs(e.g. nicotine) or viral and/or bacterial infections, and cystic .fibrosis, al though many respiratory diseases are associated with an altered mucus transport. The work presented here is a review based, amongst others,on Chatelin et al. (2015, 2016),Chatelin and Ponœt (2013, 2014, 2016),Chatelin (2013).
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