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Modeling Cystic Fibrosis and Mucociliary Clearance

Chatelin, Robin and Anne-Archard, Dominique and Murris-Espin, Marlène and Sanchez, David and Thiriet, Marc and Didier, Alain and Poncet, Philippe Modeling Cystic Fibrosis and Mucociliary Clearance. (2017) In: Modeling of Microscale Transport in Biological Processes. Elsevier, Academic Press, 113-154. ISBN 978-0-12-804595-4

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Official URL: http://dx.doi.org/10.1016/B978-0-12-804595-4.00005-5


This chapter considers the investigation of airway clearance effi.ciency and dysfonction using rheological meastll'ements, modeling and simulations of mucus flows. The work is mainly dedicated to the respiratory epithelium dysfunction subsequently to the consumption of cilia-inhibiting drugs(e.g. nicotine) or viral and/or bacterial infections, and cystic .fibrosis, al­ though many respiratory diseases are associated with an altered mucus transport. The work presented here is a review based, amongst others,on Chatelin et al. (2015, 2016),Chatelin and Ponœt (2013, 2014, 2016),Chatelin (2013).

Item Type:Book Section
Uncontrolled Keywords:
Institution:French research institutions > Centre National d'Études Spatiales - CNES (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Other partners > Université de Paris Diderot - Paris 7 (FRANCE)
Other partners > Université Pierre et Marie Curie, Paris 6 - UPMC (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Other partners > Ecole Centrale de Lyon (FRANCE)
Other partners > Centre Hospitalier Universitaire de Toulouse - CHU Toulouse (FRANCE)
Other partners > Université de Pau et des Pays de l'Adour - UPPA (FRANCE)
Laboratory name:
Agence nationale de la recherche (France)
Deposited On:27 Mar 2017 09:16

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