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Surface Area of Carbon Nanoparticles: A Dose Metric for a More Realistic Ecotoxicological Assessment

Mottier, Antoine and Mouchet, Florence and Laplanche, Christophe and Cadarsi, Stéphanie and Lagier, Laura and Arnault, Jean-Charles and Girard, Hugues A. and León, Verónica and Vázquez, Ester and Sarrieu, Cyril and Pinelli, Eric and Gauthier, Laury and Flahaut, Emmanuel Surface Area of Carbon Nanoparticles: A Dose Metric for a More Realistic Ecotoxicological Assessment. (2016) Nano Letters, 16 (6). 3514-3518. ISSN 1530-6984

(Document in English)

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Official URL: http://dx.doi.org/10.1021/acs.nanolett.6b00348


Engineered nanoparticles such as graphenes, nanodiamonds, and carbon nanotubes correspond to different allotropes of carbon and are among the best candidates for applications in fast-growing nanotechnology. It is thus likely that they may get into the environment at each step of their life cycle: production, use, and disposal. The aquatic compartment concentrates pollutants and is expected to be especially impacted. The toxicity of a compound is conventionally evaluated using mass concentration as a quantitative measure of exposure. However, several studies have highlighted that such a metric is not the best descriptor at the nanoscale. Here we compare the inhibition of Xenopus laevis larvae growth after in vivo exposure to different carbon nanoparticles for 12 days using different dose metrics and clearly show that surface area is the most relevant descriptor of toxicity for different types of carbon allotropes.

Item Type:Article
Additional Information:Thanks to ACS Publications editor. The definitive version is available at http://pubs.acs.org The original PDF of the article can be found at Nano Letters website : http://pubs.acs.org/journal/nalefd
HAL Id:hal-01346283
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Commissariat à l'Energie Atomique et aux énergies alternatives - CEA (FRANCE)
French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Other partners > Universidad de Castilla-La Mancha - UCLM (SPAIN)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
Laboratory name:
European Union Seventh Framework Programme
Deposited On:18 Jul 2016 14:06

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