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Knowledge-based modelling applied to synucleinopathies

Kamsu-Foguem, Bernard and Tiako, Pierre and Mutafungwa, Edward and Foguem, Clovis Knowledge-based modelling applied to synucleinopathies. (2015) European Geriatric Medicine (6). 381-388. ISSN 1878-7649

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Official URL: http://dx.doi.org/10.1016/j.eurger.2015.02.011


The adoption of telemedicine technologies has enabled collaborative programs involving a variety of links among distributed medical structures and health officials and professionals. The use for telemedicine for transmission of medical data and the possibility for several distant physicians to share their knowledge on given medical cases provides clear benefits, but also raises several unsolved conceptual and technical challenges. The seamless exchange and access of medical information between medical structures, health professionals, and patients is a prerequisite for the harmonious development of this new medical practice. This paper proposes a new approach of semantic interoperability for enabling mutual understanding of terminologies and concepts used. The proposed semantic interoperability approach is based on conceptual graph to support collaborative activities by describing how different health specialists can apply appropriate strategies to eliminate differential medical diagnosis. Intelligent analysis strategies are used to narrow down and pinpoint medical disorders. The model proposed is fully verified by a case study in the context of elderly patients and specifically dealing with synucleinopathies, a group of neurodegenerative diseases that include Parkinson's disease (PD), dementia with Lewy bodies (DLB), pure autonomic failure (PAF) and multiple system atrophy (MSA).

Item Type:Article
Additional Information:Thanks to Elsevier editor. The definitive version is available at : http://www.journals.elsevier.com/european-geriatric-medicine/
HAL Id:hal-01212095
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Other partners > Université de Bourgogne - UB (FRANCE)
Other partners > Aalto University (FINLAND)
Other partners > Langston University (USA)
Laboratory name:
Deposited On:21 Aug 2015 09:34

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