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Ecodesign of Batch Processes: Optimal Design Strategies for Economic and Ecological Bioprocesses

Dietz, Adrian and Azzaro-Pantel, Catherine and Pibouleau, Luc and Domenech, Serge Ecodesign of Batch Processes: Optimal Design Strategies for Economic and Ecological Bioprocesses. (2007) International Journal of Chemical Reactor Engineering, 5. ISSN 1542-6580

(Document in English)

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Official URL: http://www.bepress.com/ijcre/vol5/A34


This work deals with the multicriteria cost-environment design of multiproduct batch plants, where the design variables are the equipment item sizes as well as the operating conditions. The case study is a multiproduct batch plant for the production of four recombinant proteins. Given the important combinatorial aspect of the problem, the approach used consists in coupling a stochastic algorithm, indeed a Genetic Algorithm (GA) with a Discrete Event Simulator (DES). To take into account the conflicting situations that may be encountered at the earliest stage of batch plant design, i.e. compromise situations between cost and environmental consideration, a Multicriteria Genetic Algorithm (MUGA) was developed with a Pareto optimal ranking method. The results show how the methodology can be used to find a range of trade-off solutions for optimizing batch plant design.

Item Type:Article
Additional Information:Thanks to The Berkeley Electronic Press editor. The definitive version is available at http://www.bepress.com The original PDF of the article can be found at International Journal of Chemical Reactor Engineering website : http://www.bepress.com/ijcre/
HAL Id:hal-03594247
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:Other partners > Université Henri Poincaré-Nancy1 - UHP (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UT3 (FRANCE)
French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Other partners > Institut National Polytechnique de Lorraine - INPL (FRANCE)
Laboratory name:
Laboratoire des Sciences du Génie Chimique - LSGC (Nancy, France)
Laboratoire de Génie Chimique - LGC (Toulouse, France) - Procédés Systèmes Industriels (PSI) - Conception Optimisation Ordonnancement des Procédés (COOP)
Deposited On:13 Oct 2008 10:48

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