OATAO - Open Archive Toulouse Archive Ouverte Open Access Week

Control of brain blood flow by capillaries: a simulation study in an anatomically accurate large human vascular network

Lorthois, Sylvie and Lauwers, Frédéric Control of brain blood flow by capillaries: a simulation study in an anatomically accurate large human vascular network. (2012) In: 37ème Congrès de la Société de Biomécanique, 16 October 2012 - 19 October 2012 (Toulouse, France).

[img] (Document in English)

PDF (Author's version) - Depositor and staff only - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
142kB

Official URL: http://dx.doi.org/10.1080/10255842.2012.713680

Abstract

In this paper, the variations in cerebral blood flow induced by global or localised capillary vasodilations are studied. The results demonstrate that pericyte-mediated regulation of blood flowat capillary level would be efficient for neuro-vascular coupling. By contrast to a regulation situated at the level of arterioles (Lorthois et al. 2011b), the changes in blood volume can be highly localised in space, with the potential to be as close as possible of areas of neuronal activation. However, the changes in blood flow are much more diffuse. This imposes limits on the ultimate spatial resolution of hemodynamically based brain functional imaging techniques.

Item Type:Conference or Workshop Item (Lecture)
Additional Information:Thanks to Taylor & Francis editor. The definitive version is available at http://www.tandfonline.com This paper appears in Computer Methods in Biomechanics and Biomedical Engineering Volume 15, Supplement 1, 2012 Special Issue: Supplent 1: 37th Congress of the Societe de Biomecanique
Audience (journal):International peer-reviewed journal
Audience (conference):National conference proceedings
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
French research institutions > Institut National de la Santé et de la Recherche Médicale - INSERM (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Laboratory name:
Statistics:download
Deposited By: Sylvie LORTHOIS
Deposited On:10 Jan 2014 14:05

Repository Staff Only: item control page