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The Use of Thermal Techniques for the Characterization and Selection of Natural Biomaterials

Samouillan, Valérie and Delaunay, Florian and Dandurand, Jany and Merbahi, Nofel and Gardou, Jean-Pierre and Yousfi, Mohammed and Gandaglia, Alessandro and Spina, Michel and Lacabanne, Colette The Use of Thermal Techniques for the Characterization and Selection of Natural Biomaterials. (2011) Journal of Functional Biomaterials, vol. 2 (n° 3). pp. 230-248. ISSN 2079-4983

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Official URL: http://dx.doi.org/10.3390/jfb2030230

Abstract

In this paper we explore the ability of thermal analysis to check elastin and collagen integrity in different biomaterial applications. Differential Scanning Calorimetry (DSC) has been used to analyze the first and second order transitions of the biological macromolecules in the hydrated and dehydrated state. First, we report the characterization of control cardiovascular tissues such as pericardium, aortic wall and valvular leaflet. Their thermal properties are compared to pure elastin and pure collagen. Second, we present results obtained on two collagen rich tissues: pericardia with different chemical treatments and collagen with physical treatments. Finally, more complex cardiovascular tissues composed of elastin and collagen are analyzed and the effect of detergent treatment on the physical structure of collagen and elastin is brought to the fore.

Item Type:Article
Additional Information:Thanks to Journal of Functional Biomaterials and Mdpi. The original version is available at http://www.mdpi.com/ The original PDF of the article can be found at Journal of Functional Biomaterials website: http://www.mdpi.com/2079-4983/2/3/230
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT
Université de Toulouse > Université Paul Sabatier-Toulouse III - UPS
Other partners > Università degli Studi di Padova (ITALY)
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Deposited By:Denis Faragou

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