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Mineral maturity and crystallinity index are distinct characteristics of bone mineral

Farlay, D. and Panczer, G. and Rey, Christian and Delmas, P. and Boivin, Georges Mineral maturity and crystallinity index are distinct characteristics of bone mineral. (2010) Journal of Bone and Mineral Metabolism, vol. 28 (n° 4). pp. 433-445. ISSN 0914-8779

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Official URL: http://dx.doi.org/10.1007/s00774-009-0146-7

Abstract

The purpose of this study was to test the hypothesis that mineral maturity and crystallinity index are two different characteristics of bone mineral. To this end, Fourier transform infrared microspectroscopy (FTIRM) was used. To test our hypothesis, synthetic apatites and human bone samples were used for the validation of the two parameters using FTIRM. Iliac crest samples from seven human controls and two with skeletal fluorosis were analyzed at the bone structural unit (BSU) level by FTIRM on sections 2–4 lm thick. Mineral maturity and crystallinity index were highly correlated in synthetic apatites but poorly correlated in normal human bone. In skeletal fluorosis, crystallinity index was increased and maturity decreased, supporting the fact of separate measurement of these two parameters. Moreover, results obtained in fluorosis suggested that mineral characteristics can be modified independently of bone remodeling. In conclusion, mineral maturity and crystallinity index are two different parameters measured separately by FTIRM and offering new perspectives to assess bone mineral traits in osteoporosis.

Item Type:Article
Additional Information:Thanks to Springer. The definitive version is available at http://www.springerlink.com/ The original PDF of the article can be found at Thermochimica Acta website : http://www.springerlink.com/content/l75q2866jq815n9t/
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT
French research institutions > Institut National de la Santé et de la Recherche Médicale - INSERM
Université de Toulouse > Université Paul Sabatier-Toulouse III - UPS
Other partners > Université Claude Bernard-Lyon I - UCBL (FRANCE)
Laboratory name:
Statistics:download
Deposited By: Leila Abdelouhab

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