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Biomimetic apatite sintered at very low temperature by spark plasma sintering: Physico-chemistry and microstructure aspects

Grossin, David and Rollin-Martinet, Sabrina and Estournès, Claude and Rossignol, Fabrice and Champion, Eric and Combes, Christèle and Rey, Christian and Geoffroy, Chevallier and Drouet, Christophe Biomimetic apatite sintered at very low temperature by spark plasma sintering: Physico-chemistry and microstructure aspects. (2010) Acta Biomaterialia, vol. 6 (n° 2). pp. 577-585. ISSN 1742-7061

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Official URL: http://dx.doi.org/10.1016/j.actbio.2009.08.021

Abstract

Nanocrystalline apatites analogous to bone mineral are very promising materials for the preparation of highly bioactive ceramics due to their unique intrinsic physico-chemical characteristics. Their surface reactivity is indeed linked to the presence of a metastable hydrated layer on the surface of the nanocrystals. Yet the sintering of such apatites by conventional techniques, at high temperature, strongly alters their physico-chemical characteristics and biological properties, which points out the need for "softer" sintering processes limiting such alterations. In the present work a non-conventional technique, spark plasma sintering, was used to consolidate such nanocrystalline apatites at non-conventional, very low temperatures (T° < 300 °C) so as to preserve the surface hydrated layer present on the nanocrystals. The bioceramics obtained were then thoroughly characterized by way of complementary techniques. In particular, microstructural, nanostructural and other major physico-chemical features were investigated and commented on. This work adds to the current international concern aiming at improving the capacities of present bioceramics, in view of elaborating a new generation of resorbable and highly bioactive ceramics for bone tissue engineering.

Item Type:Article
Additional Information:Thanks to Elsevier editor. The definitive version is available at http://www.sciencedirect.com The original PDF of the article can be found at Acta Biomaterialia website : http://www.sciencedirect.com/science/journal/17427061
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:Other partners > Université de Limoges - UNILIM (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT
Université de Toulouse > Université Paul Sabatier-Toulouse III - UPS
French research institutions > Centre National de la Recherche Scientifique - CNRS
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Deposited By: Nihad Lahdifi
Deposited On:20 Jul 2010 09:36

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