Chitosan Containing Calcium Phosphate Cement: Preparation and Clinical Study

Abstract

Phosphocalcium cements have been the focus of many recent works intended to improve their properties and to extend their applications. Two points have to be addressed : their injectability and their biological degradation rate. Improvements can be made by the inclusion of synthetic or natural polymers. The healing properties and the activity on the bone regeneration of the chitosan are previously described [1]. This work relates to the re-formulation of an existing cement, CementekR, by addition of chitosan and presents the first clinical results on animal experiments.