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Artificial Gene Regulatory Networks - A Review

Cussat-Blanc, Sylvain and Harrington, Kyle and Banzhaf, Wolfgang Artificial Gene Regulatory Networks - A Review. (2019) Artificial Life, 24 (4). 296-328. ISSN 1064-5462

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Official URL: https://doi.org/10.1162/artl_a_00267

Abstract

In nature, gene regulatory networks are a key mediator between the information stored in the DNA of living organisms (their genotype) and the structural and behavioral expression this finds in their bodies, surviving in the world (their phenotype). They integrate environmental signals, steer development, buffer stochasticity, and allow evolution to proceed. In engineering, modeling and implementations of artificial gene regulatory networks have been an expanding field of research and development over the past few decades. This review discusses the concept of gene regulation, describes the current state of the art in gene regulatory networks, including modeling and simulation, and reviews their use in artificial evolutionary settings. We provide evidence forthe benefits of this concept in natural and the engineering domains.

Item Type:Article
HAL Id:hal-02092957
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Other partners > Michigan State University - MSU (USA)
Other partners > University of Idaho - UI (USA)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Université de Toulouse > Université Toulouse - Jean Jaurès - UT2J (FRANCE)
Université de Toulouse > Université Toulouse 1 Capitole - UT1 (FRANCE)
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Deposited By: IRIT IRIT
Deposited On:12 Mar 2019 09:52

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