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An intriguing relationship between the cyclic diguanylate signaling system and horizontal gene transfer

Madsen, Jonas S. and Hylling, Ole and Jacquiod, Samuel and Pécastaings, Sophie and Hansen, Lars H. and Riber, Leise and Vestergaard, Gisle and Sørensen, Søren J. An intriguing relationship between the cyclic diguanylate signaling system and horizontal gene transfer. (2018) The ISME Journal, 12 (9). 2330-2334. ISSN 1751-7362

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Official URL: https://doi.org/10.1038/s41396-018-0183-0

Abstract

The second messenger cyclic diguanylate (c-di-GMP) is ubiquitously used by bacteria to modulate and shift between different phenotypes including motility, biofilm formation and virulence. Here we show that c-di-GMP-associated genes are widespread on plasmids and that enzymes that synthesize or degrade c-di-GMP are preferentially encoded on transmissible plasmids. Additionally, expression of enzymes that synthesize c-di-GMP was found to increase both biofilm formation and, interestingly, conjugative plasmid transfer rates.

Item Type:Article
HAL Id:hal-02135635
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Other partners > Aarhus Universitet (DENMARK)
Other partners > University of Copenhagen - UCPH (DENMARK)
Laboratory name:
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Deposited By: Loetitia MOYA
Deposited On:14 Dec 2018 10:46

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