OATAO - Open Archive Toulouse Archive Ouverte Open Access Week

Powerful Antioxidant and Pro-Oxidant Properties of Cassia roxburghii DC. Leaves Cultivated in Egypt in Relation to Their Anti-Infectious Activities

El Souda, Sahar S. M. and Ibrahim, Nehal and Perio, Pierre and Ibrahim, Hany and Hénocq-Pigasse, Christel and Roques, Christine and Nepveu, Françoise Powerful Antioxidant and Pro-Oxidant Properties of Cassia roxburghii DC. Leaves Cultivated in Egypt in Relation to Their Anti-Infectious Activities. (2015) Journal of Herbs, Spices and Medicinal Plants, 21 (4). 410-425. ISSN 1049-6475

[img]
Preview
(Document in English)

PDF (Author's version) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
205kB

Official URL: https://doi.org/10.1080/10496475.2014.994084

Abstract

Leaf extracts of Cassia roxburghii DC., prepared in petroleum ether, chloroform, ethyl acetate, butanol, and methanol/water (70:30, v/v), were evaluated as antioxidant, pro-oxidant, anti-infectious, and cytotoxic agents. The major metabolite of each extract was identified by chromatographic and spectroscopic means. The redox properties were assessed with a battery of assays, which revealed that the ethyl acetate extract demonstrated an interesting scavenging activity of DPPH and superoxide radicals and an ascorbic acid-like pro-oxidant activity. All the tested extracts showed moderate antiplasmodial activity against a chloroquine-resistant strain of Plasmodium falciparum, by possible disruption of parasite fine redox balance. Cytotoxicity was evaluated against a human breast cancer cell line. The antimicrobial activities of the extracts were estimated against representative bacterial strains (Staphylococcus aureus, Enterococcus hirae, Pseudomonas aeruginosa, Escherichia coli) and fungal species (Candida albicans, Aspergillus niger). The ethylacetate extract possessed the highest redox properties and exhibited the highest antiplasmodial activity; there was no correlation between antibacterial activity and the redox properties of the extracts.

Item Type:Article
HAL Id:hal-01917335
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
French research institutions > Institut de Recherche pour le Développement - IRD (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Other partners > National Research Center - NRC (Egypt)
Laboratory name:
Statistics:download
Deposited By: Loetitia MOYA
Deposited On:08 Nov 2018 10:23

Repository Staff Only: item control page