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Bacterial colonization status of cystic fibrosis children's toothbrushes: a pilot study

Genevois, A. and Roques, Christine and Segonds, Chrsitine and Cavalié, Laurent and Brémont, François and Maubisson, Laurent and Mas, Emmanuel and Mittaine, Marie Bacterial colonization status of cystic fibrosis children's toothbrushes: a pilot study. (2015) Archives de Pédiatrie, 22 (12). 1240-1246. ISSN 0929-693X

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Official URL: https://doi.org/10.1016/j.arcped.2015.09.023

Abstract

Pseudomonas aeruginosa and Staphylococcus aureus toothbrush contamination in cystic fibrosis (CF) is unknown. This pilot study aimed to determine their prevalence and the potential involvement of toothbrushes in pulmonary infection. Methods. Toothbrush bacteriological analysis for children aged 8–18 years was conducted on 27 CF patients, 15 healthy siblings, and 15 healthy children from the general population. Results : S. aureus was detected on 22% of the patients’ toothbrushes, and 13% of healthy children's toothbrushes and P. aeruginosa on 15% of patients’ toothbrushes and 0–13% of healthy children's toothbrushes. There was no statistical correlation between pulmonary colonization and toothbrush contamination. P. aeruginosa genotyping showed two identical clones on the patients’ toothbrushes and in their sputum, and between one patient's sputum and his sibling's toothbrush. Conclusion : S. aureus and P. aeruginosa can colonize CF patients’ toothbrushes. The impact on pulmonary colonization remains unknown. Toothbrush decontamination methods need to consider these bacteria in CF patients.

Item Type:Article
HAL Id:hal-02134906
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Université de Toulouse > Université Toulouse 1 Capitole - UT1 (FRANCE)
Other partners > Centre Hospitalier Universitaire de Toulouse - CHU Toulouse (FRANCE)
Other partners > Institut Fédératif de Biologie - IFB (FRANCE)
Other partners > Université François-Rabelais de Tours (FRANCE)
Laboratory name:
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Deposited By: Loetitia MOYA
Deposited On:22 Nov 2018 16:26

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