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MRI of acute osteomyelitis in long bones of children: pathophysiology study.

Thévenin-Lemoine, Camille and Vial, Julie and Labbé, Jean-Louis and Lepage, Benoît and Ilharreborde, Brice and Accadbled, Franck MRI of acute osteomyelitis in long bones of children: pathophysiology study. (2016) Orthopaedics & Traumatology: Surgery & Research, 102 (7). 831-837. ISSN 1877-0568

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Official URL: https://doi.org/10.1016/j.otsr.2016.06.014

Abstract

INTRODUCTION: The classic pathophysiology of acute osteomyelitis in children described by Trueta has a metaphyseal infection as the starting point. This hypothesis was recently brought into question by Labbé's study, which suggested a periosteal origin. Thus, we wanted to study this disease's pathophysiology through early MRI examinations and to look for prognostic factors based on abnormal findings. MATERIAL AND METHODS: This was a prospective, multicentre study that included cases of long bone osteomyelitis in children who underwent an MRI examination within 7days of the start of symptoms and within 24hours of the initiation of antibiotic therapy. We also collected clinical, laboratory and treatment-related data. RESULTS: Twenty patients were included, including one with a bifocal condition. The lower limb was involved in most cases (19/21). Staphylococcus aureus was found most frequently. Metaphyseal involvement was present in all cases. No isolated periosteal involvement was found in any of the cases. No prognostic factors were identified based on the various abnormal findings on MRI. CONCLUSION: Our study supports the metaphyseal origin of acute osteomyelitis in children. LEVEL OF EVIDENCE:II.

Item Type:Article
Additional Information:Thanks to Elsevier editor. The definitive version is available at http://www.sciencedirect.com The original PDF of the article can be found at https://www.sciencedirect.com/science/article/pii/S1877056816300998
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:Other partners > Centre hospitalier territorial Gaston-Bourret de la Nouvelle-Calédonie (FRANCE)
Other partners > Assistance publique - Hôpitaux de Paris - AP-HP (FRANCE)
Other partners > Centre Hospitalier Universitaire de Toulouse - CHU Toulouse (FRANCE)
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Deposited By: Pascal SWIDER
Deposited On:24 Oct 2017 12:46

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