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Transcriptome of melanoma cells from two mouse models, Tyr:NRasQ61Kand Tyr:Rack1-HA, Tyr:NRasQ61K

Campagne, Cécile and Pons, Stéphanie and Esquerré, Diane and Estellé-Fabrellas, Jordi and Bourneuf, Emmanuelle and Maskos, Uwe and Egidy, Giorgia Transcriptome of melanoma cells from two mouse models, Tyr:NRasQ61Kand Tyr:Rack1-HA, Tyr:NRasQ61K. (2017) Data in Brief, 14. 32-34. ISSN 2352-3409

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Official URL: https://doi.org/10.1016/j.dib.2017.07.006

Abstract

The transcriptome sequencing of melanoma cells from two mouse models differing in the expression level of the scaffold protein Receptor for activated C kinase (RACK1) are presented. Primary melanoma cells were harvested from Tyr:NRasQ61K; Pax3GFP/+ mice, with or without the Tyr:Rack1-HA transgene. Cells were cultured and infected with scramble shRNA or Rack1-targeting shRNA, on technical triplicates of viral infection. Libraries were prepared by selecting polyadenylated mRNAs and RNA Sequencing (RNASeq) was performed. Samples are described in the SRA portal (SRP096162) and FASTQ files have been deposited in Sequence Read Archive (accession numbers: SRR5150106 to SRR5150117). The interpretation of these data is presented in the following research article: “RACK1 cooperates with NRASQ61K to promote melanoma in vivo” (Campagne et al., 2017, doi: 10.1016/j.cellsig.2017.03.015)

Item Type:Article
Additional Information:Thanks to Elsevier editor. The original PDF of the article can be found on Data in Brief website : https://www.sciencedirect.com/science/article/pii/S2352340917303086?via%3Dihub
ProdINRA Id:402590
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:Other partners > AgroParisTech (FRANCE)
French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Ecole Nationale Vétérinaire de Toulouse - ENVT (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
French research institutions > Institut National de la Recherche Agronomique - INRA (FRANCE)
Other partners > Institut Pasteur (FRANCE)
Other partners > Ecole Nationale Vétérinaire d'Alfort - ENVA (FRANCE)
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Deposited By: INRA INRA
Deposited On:17 Jan 2018 09:27

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