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Prediction of the intramembranous tissue formation during perisprosthetic healing with uncertainties. Part 1. Effect of the variability of each biochemical factor

Yang, Ji and Faverjon, Béatrice and Dureisseix, David and Swider, Pascal and Kessissoglou, Nicole Prediction of the intramembranous tissue formation during perisprosthetic healing with uncertainties. Part 1. Effect of the variability of each biochemical factor. (2016) Computer Methods in Biomechanics and Biomedical Engineering, 19 (13). 1378-1386. ISSN 1025-5842

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Official URL: http://dx.doi.org/10.1080/10255842.2016.1143464

Abstract

A stochastic model is proposed to predict the intramembranous process in periprosthetic healing in the early post-operative period. The methodology was validated by a canine experimental model. In this first part, the effects of each individual uncertain biochemical factor on the bone-implant healing are examined, including the coefficient of osteoid synthesis, the coefficients of haptotactic and chemotactic migration of osteoblastic population and the radius of the drill hole. A multi-phase reactive model solved by an explicit finite difference scheme is combined with the polynomial chaos expansion to solve the stochastic system. In the second part, combined biochemical factors are considered to study a real configuration of clinical acts.

Item Type:Article
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Other partners > Institut National des Sciences Appliquées de Lyon - INSA (FRANCE)
Other partners > University of New South Wales - UNSW (AUSTRALIA)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Laboratory name:
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Deposited By: Pascal SWIDER
Deposited On:19 Sep 2017 08:43

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