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New backing layer for transdermal drug delivery systems: coatings based on fatty acid and beeswax on chitosan films

Rullier-Birat, Bénédicte and Cazalbou, Sophie and Nassar, Maria Alejandra and Cavalie, Sandrine and Tourrette, Audrey New backing layer for transdermal drug delivery systems: coatings based on fatty acid and beeswax on chitosan films. (2015) Journal of Adhesion Science and Technology, 29 (4). 245-255. ISSN 0169-4243

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Official URL: http://dx.doi.org/10.1080/01694243.2014.981982

Abstract

Fatty acids and beeswax are known to improve barrier properties of biodegradable materials. Thanks to their hydrophobic character, they can act as a barrier against water giving to the material more occlusive properties. This work was aimed at preparing fatty acid and beeswax coatings for a transdermal drug delivery system. In order to study occlusive properties of these coatings, water vapor permeability and contact angle measurements were carried out. The most homogeneous coatings were obtained from the beeswax mixture. Coatings made from emulsified beeswax exhibit high hydrophobic properties and relatively good mechanical properties compared to chitosan film without coatings.

Item Type:Article
Additional Information:Thanks to Taylor and Francis editor. The definitive version is available at : http://www.tandfonline.com/loi/tast20
HAL Id:hal-01451889
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
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Deposited By: Christophe DROUET
Deposited On:13 Jan 2017 15:33

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