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Modeling and Optimization of Lactic Acid Synthesis by the Alkaline Degradation of Fructose in a Batch Reactor

Cabassud, Michel and Cognet, Patrick and Garcia, V and Le Lann, Marie-Véronique and Casamatta, Gilbert and Rigal, Luc Modeling and Optimization of Lactic Acid Synthesis by the Alkaline Degradation of Fructose in a Batch Reactor. (2005) Chemical Engineering Communications, vol. 192 (n° 6). pp. 758-786. ISSN 0098-6445

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Official URL: http://dx.doi.org/10.1080/009864490519852

Abstract

The present work deals with the determination of the optimal operating conditions of lactic acid synthesis by the alkaline degradation of fructose. It is a complex transformation for which detailed knowledge is not available. It is carried out in a batch or semi-batch reactor. The ‘‘Tendency Modeling’’ approach, which consists of the development of an approximate stoichiometric and kinetic model, has been used. An experimental planning method has been utilized as the database for model development. The application of the experimental planning methodology allows comparison between the experimental and model response. The model is then used in an optimization procedure to compute the optimal process. The optimal control problem is converted into a nonlinear programming problem solved using the sequencial quadratic programming procedure coupled with the golden search method. The strategy developed allows simultaneously optimizing the different variables, which may be constrained. The validity of the methodology is illustrated by the determination of the optimal operating conditions of lactic acid production.

Item Type:Article
Additional Information:Thanks to Taylor and Francis editor. The definitive version is available at http://www.informaworld.comThe original PDF of the article can be found at Chemical Engineering Communications website :http://www.informaworld.com/smpp/title~content=t713454788~link=cover
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution: Université de Toulouse > Institut National Polytechnique de Toulouse - INPT
Université de Toulouse > Université Paul Sabatier-Toulouse III - UPS
French research institutions > Centre National de la Recherche Scientifique - CNRS
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Deposited By:Hélène Dubernard

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