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Inhibition of microbial growth by carbon nanotube networks

Olivi, Massimiliano and Zanni, Elena and De Bellis, Giovanni and Talora, Claudio and Sarto, Maria Sabrina and Palleschi, Claudio and Flahaut, Emmanuel and Monthioux, Marc and Rapino, Stefania and Uccelletti, Daniela and Fiorito, Silvana Inhibition of microbial growth by carbon nanotube networks. (2013) Nanoscale, 5 (19). 9023-9029. ISSN 2040-3364

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Official URL: http://dx.doi.org/10.1039/c3nr02091f

Abstract

In the last years carbon nanotubes have attracted increasing attention for their potential applications in the biomedical field as diagnostic and therapeutic nano tools. Here we investigate the antimicrobial activity of different fully characterized carbon nanotube types (single walled, double walled and multi walled) on representative pathogen species: Gram-positive Staphylococcus aureus, Gram-negative Pseudomonas aeruginosa and the opportunistic fungus Candida albicans. Our results show that all the carbon nanotube types possess a highly significant antimicrobial capacity, even though they have a colony forming unit capacity and induction of oxidative stress in all the microbial species to a different extent. Moreover, scanning electron microscopy analysis revealed that the microbial cells were wrapped or entrapped by carbon nanotube networks. Our data taken together suggest that the reduced capacity of microbial cells to forming colonies and their oxidative response could be related to the cellular stress induced by the interactions of pathogens with the CNT network.

Item Type:Article
Additional Information:Thanks to the Royal Society of Chemistry. The definitive version is available at http://pubs.rsc.org he original PDF of the article can be found at Nanoscale website : http://pubs.rsc.org/en/Content/ArticleLanding/2013/NR/c3nr02091f#!divAbstract
HAL Id:hal-01123828
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Other partners > Università di Roma - SAPIENZA (ITALY)
Other partners > Università di Bologna (ITALY)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
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Deposited By: cirimat webmestre
Deposited On:05 Mar 2015 14:55

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