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Solid -liquid extraction of andrographolide from plants experimental study, kinetic reaction and model

Wongkittipong, Rutchadaporn and Prat, Laurent E. and Damronglerd, Somsak and Gourdon, Christophe Solid -liquid extraction of andrographolide from plants experimental study, kinetic reaction and model. (2004) Separation and Purification Technology, vol. 4 (n° 2). pp. 147-154. ISSN 1383-5866

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Official URL: http://dx.doi.org/10.1016/j.seppur.2004.02.002

Abstract

Solid - liquid extraction is performed from leaves and stems of Andrographis paniculata in ethanol - water solvent, in order to obtain andrographolide. The first part of this work concerns the acquisition of the raw plant geometric and physicochemical characteristics. Then batch experiments are done in order to study the influences of the operating parameters (temperature, nature of the solvent and particles size). Furthermore, the destruction of the solute with high temperature is also studied. In the last part, an two-shape extraction model is proposed and compared with experimental data. This model includes the shape factor of the particles population composed of stems and leaves (cylinders and plates).

Item Type:Article
Additional Information:This publication is available on http://www.sciencedirect.com/science/journal/13835866
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution: Université de Toulouse > Institut National Polytechnique de Toulouse - INPT
Université de Toulouse > Université Paul Sabatier-Toulouse III - UPS
French research institutions > Centre National de la Recherche Scientifique - CNRS
Other partners > Chulalongkorn University (THAILAND)
Laboratory name:
Laboratoire de Génie Chimique - LGC (Toulouse, France) - Réaction, mélange & séparation (RMS) - Procédés pour la Chimie Fine
Department of chemical technology (Bangkok, Thaïlande)
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Deposited By: Laurent PRAT

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