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Microscopic Aquatic Predators Strongly Affect Infection Dynamics of a Globally Emerged Pathogen

Schmeller, Dirk and Blooi, Mark and Martel, An and Garner, Trenton W.J. and Fisher, Matthew C. and Azémar, Frédéric and Clare, Frances C. and Leclerc, Camille and Jäger, Lea and Guevara-Nieto, Michelle and Loyau, Adeline and Pasmans, Franck Microscopic Aquatic Predators Strongly Affect Infection Dynamics of a Globally Emerged Pathogen. (2014) Current Biology, 24 (2). 176-180. ISSN 0960-9822

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Official URL: http://dx.doi.org/10.1016/j.cub.2013.11.032

Abstract

Research on emerging infectious wildlife diseases has placed particular emphasis on host-derived barriers to infection and disease. This focus neglects important extrinsic determinants of the host/pathogen dynamic, where all barriers to infection should be considered when ascertaining the determinants of infectivity and pathogenicity of wildlife pathogens [1–3]. Those pathogens with free-living stages, such as fungi causing catastrophic wildlife declines on a global scale [4], must confront lengthy exposure to environmental barriers before contact with an uninfected host [5–8]. Hostile environmental conditions therefore have the ability to decrease the density of infectious particles, reducing the force of infection and ameliorating the impact as well as the probability of establishing an infection [9]. Here we show that, in nature, the risk of infection and infectious burden of amphibians infected by the chytrid fungus Batrachochytrium dendrobatidis (Bd) have a significant, site-specific component, and that these correlate with the microfauna present at a site. Experimental infections show that aquatic microfauna can rapidly lower the abundance and density of infectious stages by consuming Bd zoospores, resulting in a significantly reduced probability of infection in anuran tadpoles. Our findings offer new perspectives for explaining the divergent impacts of Bd infection in amphibian assemblages and contribute to our understanding of ecosystem resilience to colonization by novel pathogens.

Item Type:Article
Additional Information:Thanks to Elsevier editor. The original PDF of the article can be found at Current Biology website : http://www.cell.com/current-biology/home
HAL Id:hal-00994386
Audience (journal):International peer-reviewed journal
Uncontrolled Keywords:
Institution:French research institutions > Centre National de la Recherche Scientifique - CNRS (FRANCE)
Université de Toulouse > Institut National Polytechnique de Toulouse - INPT (FRANCE)
Université de Toulouse > Université Toulouse III - Paul Sabatier - UPS (FRANCE)
Other partners > Helmholtz-Zentrum für Umweltforschung - UFZ (GERMANY)
Other partners > Imperial College London (UNITED KINGDOM)
Other partners > Universiteit Gent - UGENT (BELGIUM)
Other partners > Zoological Society of London - ZSL (UNITED KINGDOM)
Laboratory name:
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Deposited By: Frédéric Azémar
Deposited On:21 May 2014 12:19

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